Is It Too Late to Buy?

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Is It Too Late to Buy?

Few companies have attracted more attention this year than Nvidia. The chipmaker is on a roll thanks to the rapid rise of artificial intelligence, and its revenue, earnings, and stock price continue to grow incredibly fast. Nvidia’s shares are up by 137% this year.

Some companies have performed even better, including one many investors may never have heard about: Summit Therapeutics (NASDAQ: SMMT). The biotech’s performance this year makes Nvidia’s look mediocre: Summit’s shares are up by almost 900% year to date.

What exactly is driving this performance? Are Summit Therapeutics’ shares still attractive? Let’s find out.

data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///ywAAAAAAQABAAACAUwAOw==Summit is taking on a giant

Summit focuses on developing ******* medicines. As is usually the case when a drugmaker rises this fast, it owes its recent run of form to excellent clinical progress related to its leading pipeline candidate, ivonescimab.

Originally developed by a China-based company called Akeso, Summit entered into an agreement with the former to license the ***** in certain countries, including the U.S., in exchange for an up-front payment, potential development and sales milestones, and royalties. Ivonescimab is already approved in China for a particular variant of lung *******.

It recently aced a phase 3 clinical trial in the country in treating another variant of non-small cell lung ******* (NSCLC). Ivonescimab was pitted against Merck’s Keytruda, the standard of care in NSCLC and the best-selling ***** in the world since last year, in this phase 3 study.

In the trial, ivonescimab led to a median progression-free survival of 11.14 months, compared to Keytruda’s 5.82 months. It also reduced the risk of ******** progression or ****** by 49% compared to Keytruda and posted a similar safety profile.

According to Summit, ivonescimab is the first ***** to post better clinical results than Keytruda in a phase 3 study in NSCLC.

Ivonescimab’s potential

Although Keytruda has earned dozens of indications worldwide, NSCLC is unquestionably one of its biggest growth drivers. According to the World Health Organization, lung ******* was the second most-common ******* in the world as of 2020. However, it was the leading cause of ******* ******.

About 85% of lung ******* cases are of the NSCLC variety. In 2017, about 40% of Keytruda’s sales came from the various indications it has earned in treating NSCLC, although that has likely changed as the *****’s indications expanded.

But using this as a baseline, and considering that Keytruda generated $25 billion in sales last year, about $7 billion to $10 billion of it could have come from NSCLC indications. Ivonescimab, if approved in the U.S., Canada, Japan, and other countries where Summit owns the rights to license it, could capture much of that revenue and redirect it toward Summit’s financials.

Story continues

The medicine is also being investigated in other indications, including colorectal *******, the second leading cause of ******* ****** in the world.

Is Summit a buy?

There is no question that Summit has a winner in ivonescimab, a medicine that could become a “pipeline in a *****,” just like Keytruda. The problem for investors is that the market has already priced some of ivonescimab’s success into the shares. Despite not having a single ***** on the market, the company is worth $17 billion. The stock could fall off a cliff at these levels if anything goes wrong with its leading pipeline candidate.

The good news is that funding likely won’t be an issue. Summit ended the second quarter with $325.8 million in cash and equivalents, which the company said could help it run its operations until the fourth quarter of 2025. Since then, it

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, taking advantage of ivonescimab’s recent success.

Summit Therapeutics does look a little risky, but ivonescimab’s potential makes it worth it for

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who can stomach the risk. If the company can continue posting ivonescimab-related wins, the stock might be highly lucrative in the long run.

Should you invest $1,000 in Summit Therapeutics right now?

Before you buy stock in Summit Therapeutics, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 

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for investors to buy now… and Summit Therapeutics wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Nvidia made this list on April 15, 2005… if you invested $1,000 at the time of our recommendation, you’d have $710,860!*

Stock Advisor provides investors with an easy-to-follow blueprint for success, including guidance on building a portfolio, regular updates from analysts, and two new stock picks each month. The Stock Advisor service has more than quadrupled the return of S&P 500 since 2002*.

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*Stock Advisor returns as of September 16, 2024

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has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Merck, Nvidia, and Summit Therapeutics. The Motley Fool has a

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was originally published by The Motley Fool

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#Late #Buy

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