Neurocrine halts development of schizophrenia drug as trial fails, ET HealthWorld

[Pelican Press 0]

This is the hidden content, please

• Sign In
• or
• Sign Up

Neurocrine halts development of schizophrenia ***** as trial fails, ET HealthWorld

data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///ywAAAAAAQABAAACAUwAOw==

London: Neurocrine Biosciences said on Thursday it will halt the development of its experimental *****, aimed at improving cognitive function in patients with schizophrenia, after it did not achieve the primary goal in a mid-stage trial.

The company said the *****, luvadaxistat, did not replicate the results from a previous mid-stage trial that showed improved cognitive performance, due to a large variability in the cognitive measures across the patients and a potential imbalance in their baseline characteristics.

In the previous study, luvadaxistat ******* to meet the main goal of change from baseline in negative symptoms of schizophrenia, however, it met the secondary goal of improving cognitive performance.

Neurocrine said it will focus its resources on late-stage development of its other schizophrenia and depression ***** candidates.

Shares of the company were down 2.5 per cent in extended trading.

Last month, the company said its other schizophrenia *****, NBI-1117568, helped reduce the severity of symptoms in a mid-stage trial, but there were concerns whether the benefit could be replicated in larger trials.

(Reporting by Puyaan Singh; Editing by Mohammed Safi Shamsi and Shinjini Ganguli)

• Published On Sep 13, 2024 at 07:05 AM IST

Join the community of 2M+ industry professionals

Subscribe to our newsletter to get latest insights & analysis.

data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///ywAAAAAAQABAAACAUwAOw==

Download ETHealthworld App

• Get Realtime updates
• Save your favourite articles

data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///ywAAAAAAQABAAACAUwAOw==

data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///ywAAAAAAQABAAACAUwAOw==

Scan to download App
data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///ywAAAAAAQABAAACAUwAOw==

This is the hidden content, please

• Sign In
• or
• Sign Up

#Neurocrine #halts #development #schizophrenia #***** #trial #fails #HealthWorld

This is the hidden content, please

• Sign In
• or
• Sign Up

This is the hidden content, please

• Sign In
• or
• Sign Up