Scientists Destroy 99% of Cancer Cells in Lab With Vibrating Molecules

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Scientists ******** 99% of ******* Cells in Lab With Vibrating Molecules

Scientists have discovered a remarkable way to ********

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. Stimulating

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with near-infrared light caused them to vibrate in sync, enough to break apart the membranes of

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cells.

Aminocyanine molecules are already used in bioimaging as synthetic dyes. Commonly used in low doses to detect *******, they stay stable in water and are very good at attaching themselves to the outside of cells.

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The research team from Rice University, Texas A&M University, and the University of Texas, said their approach is a marked improvement over another kind of *******-******** molecular machine

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called Feringa-type motors, which could also break the structures of problematic cells.

“It is a whole new generation of molecular machines that we call molecular jackhammers,”

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chemist James Tour from Rice University, when the results were published in December 2023.

“They are more than one million times faster in their mechanical motion than the former Feringa-type motors, and they can be activated with near-infrared light rather than visible light.”

The use of near-infrared light is important because it enables scientists to get deeper into the body. ******* in bones and organs could potentially be treated without needing surgery to get to the

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.

In tests on cultured, lab-grown ******* cells, the molecular jackhammer method scored a 99 percent hit rate at destroying the cells. The approach was also tested on mice with

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, and half the animals became *******-free.

The structure and chemical properties of aminocyanine molecules mean they stay in sync with the right stimulus – such as near-infrared light. When in motion, the electrons inside the molecules form what’s known as

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, collectively vibrating entities that drive movement across the whole of the molecule.

“What needs to be highlighted is that we’ve discovered another explanation for how these molecules can work,”

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chemist Ciceron Ayala-Orozco from Rice University.

“This is the first time a molecular plasmon is utilized in this way to excite the whole molecule and to actually produce mechanical action used to achieve a particular goal – in this case, tearing apart ******* cells’ membrane.”

The plasmons have an arm on one side, helping to connect the molecules to the

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membranes while the movements of the vibrations bash them apart. It’s still early days for the research, but these initial findings are very promising.

This is also the kind of straightforward, biomechanical technique that ******* cells would find it hard to evolve some sort of

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. Next, the researchers are looking at other types of molecules that can be used similarly

“This study is about a different way to treat ******* using mechanical forces at the molecular scale,”

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Ayala-Orozco.

The research was published in

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.

An earlier version of this article was published in December 2023.

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#Scientists #******** #******* #Cells #Lab #Vibrating #Molecules

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